NC College/University Vaccine Requirements and Number of Doses
| Vaccine | Number of Doses |
| Diphtheria, Tetanus and/or Pertussis1 | 3 |
| Polio2 | 3 |
| Measles3 | 2 |
| Mumps4 | 2 |
| Rubella5 | 1 |
| Hepatitis B6 | 3 |
Footnote 1 - DTP (Diphtheria, Tetanus, Pertussis), DTaP (Diphtheria, Tetanus, acellular Pertussis), Td (Tetanus, Diphtheria), Tdap (Tetanus, Diphtheria, Pertussis): 3 doses of tetanus/diphtheria toxoid of which one must have been within the past 10 years.
Those individuals enrolling in college or university for the first time on or after July 1, 2008 must have had three doses of tetanus/diphtheria toxoid and a booster dose of tetanus/diphtheria/pertussis vaccine if a tetanus/diphtheria toxoid or tetanus/diphtheria/pertussis vaccine has not been administered within the past 10 years.
Footnote 2 - An individual attending school who has attained his or her 18th birthday is not required to receive polio vaccine.
Footnote 3 - Measles vaccines are not required if any of the following occur: Diagnoses of disease prior to January 1, 1994; An individual who has been documented by serological testing to have a protective antibody titer against measles; or An individual born prior to 1957. An individual who enrolled in college or university for the first time before July 1, 1994 is not required to have a second dose of measles vaccine.
Footnote 4 - Mumps vaccine is not required if any of the following occur: An individual who has been documented by serological testing to have a protective antibody titer against mumps; An individual born prior to 1957; or Enrolled in college or university for the first time before July 1, 1994. An individual entering college or university prior to July 1, 2008 is not required to receive a second dose of mumps vaccine.
Footnote 5 - Rubella vaccine is not required if any of the following occur: 50 years of age or older; Enrolled in college or university before February 1, 1989 and after their 30th birthday; An individual who has been documented by serological testing to have a protective antibody titer against rubella.
Footnote 6 - Hepatitis B vaccine is not required if any of the following occur: Born before July 1, 1994.

